ß-amyloid influences [18F]AV-1451 uptake in patients with primary progressive aphasia

Takeaway

  • [18F]AV-1451 uptake in people with the semantic variant of primary progressive aphasia (svPPA) is lower than in people with Alzheimer’s disease, but uptake was greater in people with svPPA who were ß-amyloid (Aß)+.

Why this matters

  • The presence of Aß is considered a biomarker for Alzheimer’s disease.