7T MRI as a tool to detect disturbed cortical lamination in patients with Alzheimer’s disease

Takeaway

  • 7T MRI detected visible cortical lamination in Alzheimer’s disease (AD) patients and severely distorted cortical lamination in selective regions of the medial temporal lobe (MTL) in advanced stage AD patients.

Why this matters

  • Changes in the patterns of cortical lamination in AD patients by 7T MRI have not been previously explored and may provide additional diagnostic and prognostic tools for AD.