Are biomarkers for Alzheimer’s Disease influenced by racial differences?

Takeaway

  • African American individuals with an Apolipoprotein E (APOE ε4) genotype had lower levels of Alzheimer’s Disease (AD)-specific biomarkers and smaller hippocampal volumes in those with a history of dementia when compared with white participants.

Why this matters

  • It is important to determine whether race influences AD-specific characteristics to inform future diagnostic and therapeutic measures for the disease.