A Delphi consensus of cerebrovascular autoregulation monitoring in severe traumatic brain injury


  • Twenty-five consensus statements addressing the pathophysiology of impaired cerebrovascular autoregulation (CA) and its effect on cerebral perfusion pressure (CPP) targets and outcome resulted from the Delphi procedure.

Why this matters

  • There is a lack of a gold standard and prospective data regarding secondary brain injury risks, impact on care and outcomes of implementation of CA-guided management in severe traumatic brain injury (TBI) treatment, leading to uncertainty.

  • The identification of multiple consensus statements addressing CA-guided management of patients with severe TBI highlights the need for prospective clinical studies examining the feasibility, safety and efficacy of this methodology in this particular cohort.