A magnetic resonance imaging-based prediction model lateralizes hippocampal sclerosis in temporal lobe epilepsy


  • A prediction model for temporal lobe epilepsy lateralization operates on conventional magnetic resonance imaging contrasts and is more accurate than visual radiological assessment.

Why this matters

  • Magnetic resonance imaging cannot identify hippocampal pathology in up to 50% of temporal lobe epilepsy surgical candidates. This is the first report of a decision-support system that can lateralize hippocampal sclerosis in temporal lobe epilepsy using structural magnetic resonance imaging. Providing a non-invasive decision-support, advanced imaging analysis can bypass some of the limitations and risks associated with invasive diagnostics in temporal lobe epilepsy.