A mutation in CASP7 is linked to familial late-onset Alzheimer’s disease

Takeaway 

  • A CASP7 gene variant is associated with late-onset Alzheimer’s disease (AD); this provides further evidence for the role of caspase apoptotic pathways in AD.

Why this matters

    With AD incidence set to substantially rise over coming decades, identification of AD-related genes is important to further understand the disease and highlight new drug targets.