A novel approach to identifying diagnostic markers in trigeminal neuralgia


  • Patients with trigeminal neuralgia (TN) exhibit structural brain alterations, including reductions in cortical indices and widespread subcortical volume reduction.

Why this matters

  • Magnetic resonance imaging (MRI) is used in patients with TN to determine the etiology of the condition (primary or secondary TN) and the degree of trigeminal nerve root compression.

  • The findings of this study, in which the researchers developed a machine learning model to evaluate imaging markers that could differentiate between brain images of patients with TN and those of healthy controls, have the potential to guide future development of appropriate treatments.