A preclinical study on the role of cortical circuits in epileptic spasm generation

Takeaway

  • Neuronal activity in the cortex contributed to the generation of epileptic spasms in a rat model of epilepsy.

Why this matters

    The neurophysiology underlying epileptic spasms is unknown, however, the contributing role of cortical cells and circuits has been debated and further studies are needed to understand this association.