A retrospective study characterizing tumefactive multiple sclerosis


  • While those with tumefactive multiple sclerosis (TuMS) have a more severe clinical presentation at onset than multiple sclerosis (MS), similarities with MS support the classification of TuMS as a variant of MS rather than a distinct disease.

Why this matters

    The disease course and best management strategies for TuMS, an atypical MS presentation with tumefactive demyelinating lesions (TDLs), are unclear. This characterization of TuMS emphasizes the need for large, long-term, prospective studies on TuMS to identify optimal treatment strategies.