Acquired and heritable factors influence age at symptomatic onset of Alzheimer’s disease

Takeaway

  • Both acquired and heritable factors contribute to the wide variation in age at symptomatic onset of Alzheimer’s disease.

Why this matters

    Identifying the link between acquired and heritable factors with variability in intergenerational age of symptomatic onset of Alzheimer’s disease could support diagnosis and counseling of offspring of affected parents who are at high risk of developing dementia.