Acute-onset delirium in severe COVID-19 and associations with foodborne micro-pollutants


  • A subset of patients with coronavirus 19 (COVID-19) are at risk of a specific type of delirium associated with imperfect brain repair and pre-infection lifestyle factors.

Why this matters

  • Neuroimaging and cerebrospinal fluid (CSF) analyses in patients with COVID-19 requiring ventilation have revealed severe brain injury and inflammatory profiles; however, their pathophysiology and interaction are poorly understood.

  • The link between brain injury, delirium and foodborne micropollutants in COVID-19 may potentially provide insight into the influence of pre-infection lifestyle factors on patient outcomes, adding further insight into pathophysiological mechanisms of the virus.