Age and autoantibody serostatus in individuals with late-onset neuromyelitis optic spectrum disorder

Takeaway

  • The main predictors of the outcome of individuals with late onset neuromyelitis optic spectrum disorder (LO-NMOSD) are serostatus and residual disability after the first attack.

Why this matters

    Few studies have investigated the effects and outcomes when NMOSD is presented at an older age. This study demonstrates that the serostatus of an individual is important to consider when assessing the risk of developing an ambulatory disability.