Altered brain network topology in the limbic system in euthymic bipolar disorder

Takeaway

  • Investigation of resting‐state functional magnetic resonance imaging (fMRI) with graph theoretical network analyses revealed significantly altered brain network topology in the limbic system as a trait marker specific to bipolar disorder (BD).

Why this matters

  • BD and major depressive disorder (MDD) manifest highly similar in depressive episodes; brain network analysis of the limbic system could be used to differentiate euthymic BD from patients with MDD and healthy controls (HC).