Alzheimer-like neurodegeneration associated with cognitive impairment in temporal lobe epilepsy

Takeaway

  • A link between hyperexcitability in epilepsy and amyloid and tau-related neurodegeneration could explain cognitive impairment in drug-resistant temporal lobe epilepsy.

Why this matters

    Novel therapeutic interventions targeting amyloid and tau-related pathways could help to prevent cognitive decline in temporal lobe epilepsy.