Alzheimer’s disease and Lewy body disease have distinct effects on subcortical atrophy and cognition

Takeaway

  • Alzheimer’s disease (AD) and Lewy body disease (LBD) independently contribute to subcortical atrophy in a disease-specific manner; the effects of this atrophy on cognitive dysfunction differ according to underlying causes of cognitive impairment.

Why this matters

    Further investigations into subcortical atrophy and its correlation with cognitive deficits may enhance our understanding of underlying causes of cognitive dysfunction.