Analysis of atypical symmetry and atrophy in temporal lobe epilepsy

Takeaway

  • Atypical inter-hemispheric asymmetry analysis revealed an ipsilateral limbic signature, and cortical thickness mapping demonstrated widespread and bilateral atrophy in temporal lobe epilepsy (TLE) pathology. 

Why this matters

  • Atypical symmetry and regional atrophy measures in TLE have not been well studied.

  • Results from this study advance clinical understanding of TLE pathology and may aid in the detection and authentication of neuroimaging biomarkers.