Analysis of axonal injury and neurodegeneration following traumatic brain injury

Takeaway

  • Severity and location of diffuse axonal injury was a strong predictor of post-traumatic neurodegeneration following traumatic brain injury (TBI).

Why this matters

  • The mechanisms which underlie post-traumatic neurodegeneration are poorly understood. This study provides evidence for the causal link between diffuse axonal injury and brain atrophy following TBI.