Analysis of brain network alterations in mild cognitive impairment and Alzheimer’s disease

Takeaway

  • Applying graph theoretical analysis to diffusion tensor imaging (DTI) and resting state magnetic resonance imaging (rs-fMRI) data provides insight into degradation of network topology in mild cognitive impairment (MCI) and Alzheimer’s disease (AD).

Why this matters

  • Use of a multiparametric network analysis framework, incorporating multiple structural and functional connectivity metrics, may facilitate early diagnosis of MCI and prevention of AD.