Analysis of neuroinflammation prevalence in people taking TNF-alpha inhibitors

Takeaway

  • While neuroinflammation following tumor necrosis factor alpha inhibitors (TNFi) is a common concern for those treating patients with autoimmune disease, this study found that TNFi-associated inflammation was a rare outcome in the population analyzed.

Why this matters

    The TNF blockade has been associated with worsening of multiple sclerosis (MS) in a small number of cases, leading to reluctance in use by physicians.