APOE ε4 carrier status in those with aphasic and amnesic variants of Alzheimer’s disease


  • There were increased proportions of APOE ε4 carriers in those with amnesic Alzheimer’s disease (AD), but not those with aphasic-presenting AD.

Why this matters

    The increase in APOE ε4 carriers in the amnesic group indicates that this biomarker is a risk factor for increased susceptibility to AD pathology in medial temporal areas.