Takeaway
The amyloid-beta (A), tau (T) and neurodegeneration (N) (ATN) classification system provides varied results depending on method used to assess biomarkers.
Why this matters
The National Institute on Aging and Alzheimer’s Association has proposed a framework suggesting the ATN biomarkers be compiled to a single classification system.
It is unknown how ATN testing approaches affect category prevalence or affect the ability of ATN to act as a predictor of cognitive decline.