Are specific surgical lesions associated with favorable outcomes in temporal lobe epilepsy?


  • In patients with temporal lobe epilepsy (TLE) who underwent surgical treatment, better outcomes at 12 months post-surgery were associated with surgical lesions of specific structures and connections in the temporal lobe.

Why this matters

  • Although surgery for TLE can result in seizure freedom, up to 40% of patients continue to have seizures with awareness loss.

  • This study may contribute to future improvements in surgical intervention by highlighting key components of epileptogenic networks in TLE.