Articulation rate: an effective way to assess motor speech impairment in primary progressive aphasia


  • Articulation rate is an effective method for assessing primary progressive aphasia (PPA) and can be used to detect mild disease as well as decline over time; it is particularly sensitive in the detection of nonfluent PPA (nfvPPA).

Why this matters

  • Motor speech impairment (MSI) is a key feature of clinical variants of PPA and is indicative of underlying tauopathy, therefore accurate quantitative assessment of MSI is vital.