Assessing upper airway collapsibility with a simple wakefulness test in obstructive sleep apnea


  • The upper airway collapsibility measured during a 10-minute wakefulness test to brief pulses of negative airway pressure (upper airway collapsibility index [UACI]), is strongly correlated with pharyngeal collapsibility during sleep in people with a wide range of obstructive sleep apnea (OSA) severity.

Why this matters

    The critical closing pressure (Pcrit) technique is the gold standard for quantifying airway collapsibility, but it is labor intensive which impedes its use in everyday clinical practice; this study highlights the potential of the UACI as a simple, alternative tool for clinical use.