Assessment of longitudinal white matter abnormalities in sports-related concussion


  • White matter abnormalities in sports-related concussion (SRC) persist post-injury even after resolution of clinical symptoms; severity of white matter injury is associated with worse clinical outcomes and prolonged recovery time.

Why this matters

  • Millions of sports- and recreation-related concussions occur each year in high school and collegiate athletes, but the natural history of these injuries and their pathophysiologic recovery time course is unclear.

  • Awareness of SRC brain abnormalities that persist beyond clinical presentation could impact current management of these injuries as well as relevant protocols in, and monitoring of, collegiate contact sports.