Association between gut microbiome composition and pain perception in young, healthy male volunteers


  • Acute pain perception is associated with gut microbiome composition in young, healthy males.

Why this matters

  • Gut microbiome has been implicated in numerous diseases, including Parkinson’s disease and Alzheimer’s disease. Growing evidence also supports the role of gut microbiome in psychiatric diseases, such as anxiety and depression.

  • This study revealed that different types of pain demonstrated associations with different gut microbiome compositions. Examining the metabolites produced by these gut microbiome bacteria may help elucidate the mechanisms by which gut microbiome can influence pain perception.