Association between vaccines, infectious disease and CNS demyelination

Takeaway

  • CNS demyelination is more common in those who receive poliomyelitis vaccination before pre-school, “late” rubella vaccination, or “late” infectious mononucleosis.

Why this matters

    Evidence for the association of childhood infections/vaccinations and development of multiple sclerosis (MS) is inconsistent and few studies have considered age at vaccination/ infection.