Associations Between Sleep Quality and Risk for Alzheimer’s Disease


  • Increased sleep disturbances measured by actigraphy are associated with increased amyloid beta load.

Why this matters

  • Sleep disturbances are associated with a 1.5-fold increased risk in developing Alzheimer’s disease (AD) and an increase in amyloid pathology.

  • Objectively measuring sleep disturbances may predict amyloid beta load and the risk of developing AD; however, this association has not been thoroughly studied.