Takeaway
Increased sleep disturbances measured by actigraphy are associated with increased amyloid beta load.
Why this matters
Sleep disturbances are associated with a 1.5-fold increased risk in developing Alzheimer’s disease (AD) and an increase in amyloid pathology.
Objectively measuring sleep disturbances may predict amyloid beta load and the risk of developing AD; however, this association has not been thoroughly studied.