Biological clock disruptions in patients with obstructive sleep apnea


  • Obstructive sleep apnea (OSA) alters biological clock-related characteristics that differentially respond to short- and long-term continuous positive airway pressure (CPAP) treatment.

Why this matters ?

  • OSA is one of the most prevalent sleep disorders which, when left untreated, is associated with the development of a wide range of comorbidities, including hypertension and metabolic disease.

  • The potential effect of OSA on the disruption of the biological clock has been implicated in exacerbating or playing a causal role in these adverse outcomes associated with OSA.