Biomarkers of oxidative stress in women with obstructive sleep apnea


  • After 12 weeks of continuous positive airway pressure (CPAP) therapy there was no change in levels of circulating biomarkers of inflammation, oxidation, or depression in women with obstructive sleep apnea (OSA).

Why this matters

  • OSA is an important risk factor for comorbidities such as cardiovascular disease, hypertension, depression and worsened quality of life.

  • The intermittent hypoxia (IH) that is typical of OSA causes an increase in reactive oxygen species leading to inflammation and oxidative stress, however whether CPAP therapy can improve biomarkers of these activities is unknown.