Brain changes identified 2 years before symptom onset in familial frontotemporal dementia

Takeaway

  • Multimodal magnetic resonance imaging (MRI) can detect brain changes in presymptomatic familial frontotemporal dementia (FTD).

Why this matters

  • This study further characterizes disease trajectories for familial FTD and highlights the value of multimodal MRI as a prognostic biomarker.