Brain-derived exosome levels in peripheral plasma correlate to Parkinson’s disease severity

Takeaway

  • A newly developed assay suggests that increased plasma levels of select brain-derived exosomes correlate to Parkinson’s disease (PD) and other parkinsonism-related diseases.

Why this matters

  • Diagnosis of early stage PD remains a challenge, and this non-invasive, blood-based assay measuring exosome levels has potential to be used as a biomarker for PD.