Brain imaging and anosmia in patients with COVID-19

Takeaway

  • Olfactory function loss (OFL) in patients with COVID-19 is associated with a reversible obstruction of the olfactory clefts (OC).

Why this matters ?

  • The underlying mechanisms of transient anosmia, commonly associated with the SARS-CoV2 infection COVID-19, are not fully understood; however, the virus is known to interact with ACE2 proteins, which are expressed in the olfactory epithelium (OE).

  • Understanding the underlying mechanisms of COVID-19-associated pathology is vital for the development of therapeutics and potential vaccines, especially given the ongoing catastrophic mortality, socioeconomic and financial burden of COVID-19 worldwide.