Brain metabolic impairment in Lewy Body dementia

Takeaway

  • The core clinical features of dementia with Lewy Bodies (DLB) are associated with hypometabolism in specific regions of the brain, as assessed by FDG-positron emission tomography (PET).

Why this matters

  • FDG-PET is emerging tool in clinical practice to assess patterns of regional brain metabolism deficits, and after optimization may be useful in DLB as well as other neurodegenerative diseases.