Brain structure and pain in localized provoked vestibulodynia

Takeaway

  • Gray matter volume (GMV) varies in provoked vestibulodynia (PVD) compared with healthy controls (HC) in several regions and shows distinct alterations compared with irritable bowel syndrome (IBS).

Why this matters

  • Mapping brain region differences between chronic pain sufferers of both visceral and somatic pain and HC may lead to better understanding of the pathophysiological mechanisms involved.