Can cerebello-spinal stimulation improve symptoms in patients with neurogenerative ataxias?


  • Cerebello-spinal transcranial direct current stimulation (tDCS) improved motor and cognitive symptoms in patients with neurogenerative ataxias and could be a potential new treatment in this patient population.

Why this matters

  • Neurodegenerative ataxias consist of several heterogenous disabling progressive diseases for which effective treatments are currently lacking.

  • Although research has shown that tDCS is effective in promoting neuroplasticity and improving symptoms in patients with neurodegenerative ataxia, including the authors’ pilot study in which cerebello-spinal tDCS led to the restoration of cerebellar inhibition (CBI), a number of unmet needs remain.

  • This study provides supporting evidence for the effectiveness of tDCS in treating neurodegenerative ataxias using transcranial magnetic stimulation (TMS) and is a promising new treatment for these disabling diseases.