Can dysfunction of the blood brain barrier contribute to refractory epilepsy?

Takeaway 

  • Patients with post-encephalitic/encephalopathic epilepsy (PEE) show chronic blood brain barrier (BBB) dysfunction associated with refractory epilepsy. 

Why this matters

    By understanding the impact of PEE on the BBB, further research may lead to the development of therapies to improve the prognosis of refractory patients with BBB dysfunction.