Category-selective semantic memory deficit for animate objects is common in semantic variant primary progressive aphasia

Takeaway

  • A category-selective semantic deficit for animate objects is a common feature of semantic variant primary progressive aphasia and is linked to greater cortical atrophy in the right temporal lobe.

Why this matters

  • The link between semantic variant primary progressive aphasia and neural substrates of category-selective semantic deficits is currently unclear. The imaging findings of this novel study highlight the role of the right perirhinal cortex and other temporal lobe regions in the semantic processing of animate objects. Greater understanding of the degeneration of semantic memory will elucidate how these individuals interpret the world around them which will assist with interventional strategies and management.