Cerebrospinal fluid pleocytosis and disease course in multiple sclerosis

Takeaway

  • Cerebrospinal fluid (CSF) pleocytosis may be considered a biological unfavorable predictive factor regarding disease course and progression in multiple sclerosis (MS).

Why this matters

  • CSF pleocytosis at presentation of MS might serve as a biological marker reflecting a more active inflammatory process and thus might indicate an active immunosuppressive therapy in the future.