Cerebrovascular response to moderate aerobic exercise is modified in Huntington’s disease

Takeaway

  • Compared with healthy people, a single session of moderate exercise leads to a transient regionally-specific increase in cerebral perfusion in those with Huntington’s disease.

Why this matters

    This model could help to reveal the key components that enable exercise to alter a pathologically disturbed cerebrovasculature which could ultimately lead to novel therapies in Huntington’s disease.