Change in myo-inositol levels in the brain could be a marker of future cognitive decline

Takeaway

  • Changes in myo-inositol (mI)/creatine (Cr) and N-acetylaspartate (NAA)/MI levels are associated with increased amyloid pathology.

Why this matters ?

  • Measures of myo-inositol have the potential to be a widely available, cost-effective and non-invasive marker for identifying predementia and monitoring disease progression.