Changes in interleukin-9 linked to development of Alzheimer’s disease in African Americans

Takeaway

  • The relative change in inflammatory biomarker levels such as interleukin-9 (IL-9) in African Americans may underpin a genetic component of increased risk of Alzheimer’s disease (AD).

Why this matters

    African Americans are twice as likely as Caucasians to develop AD, yet potential differences in pathologic mechanisms are unclear due to lack of available tissue samples. Better understanding of genetic factors that contribute to cognitive decline may influence future research as well as treatment decisions.