Characteristics of Progressive Agrammatic Aphasia Syndrome


  • Progressive agrammatic aphasia (PAA) has distinct clinical and neuroimaging characteristics and should be a separately classified syndrome from mixed agrammatism and apraxia of speech (AOS).

Why this matters

  • Typically, people are diagnosed with Primary Progressive Aphasia (agPPA) when they demonstrate either agrammatic aphasia, apraxia of speech (AOS), or both.

  • Very little is known about the course of agrammatic aphasia alone, which leads to ineffective research and treatments.