Characteristics of protein aggregates in patients with Parkinson’s disease

Takeaway

  • Protein aggregates found in serum of patients with Parkinson’s disease (PD) could be a potential early-disease diagnostic biomarker for PD.

Why this matters ?

  • Protein aggregates, found in the brain, blood, and cerebrospinal fluid (CSF), play a key role in the development of PD.

  • Research into the characteristics of these aggregates may provide a better understanding of the PD mechanisms and facilitate the diagnosis.

  • This study identified the differences in size and chemical composition of protein aggregates in patients with early PD and those found in healthy controls (HC) – a finding that may aid clinicians in early diagnosis of PD.