Protein aggregates found in serum of patients with Parkinson’s disease (PD) could be a potential early-disease diagnostic biomarker for PD.
Why this matters ?
Protein aggregates, found in the brain, blood, and cerebrospinal fluid (CSF), play a key role in the development of PD.
Research into the characteristics of these aggregates may provide a better understanding of the PD mechanisms and facilitate the diagnosis.
This study identified the differences in size and chemical composition of protein aggregates in patients with early PD and those found in healthy controls (HC) – a finding that may aid clinicians in early diagnosis of PD.