Characterization and risk factor analysis of coagulopathy in isolated traumatic brain injury


  • People with isolated traumatic brain injury (iTBI) who were treated pre-injury with antiplatelet and/or anticoagulant therapy had a greater frequency of coagulopathy compared with those who were untreated. Several independent risk factors that were associated with acute coagulopathy following iTBI were also identified.

Why this matters

    In some people, iTBI can lead to coagulopathy which increases the risk of adverse clinical outcomes and mortality. A more thorough understanding of the hemostatic alterations that occur in iTBI may enhance the efficacy of risk assessment and clinical management after trauma.