Characterization of neuropathic-like pain in adults with or at risk of knee osteoarthritis


  • Individuals with, or at risk of, knee osteoarthritis (OA) with high neuropathic-like pain (NLP) reported significantly greater clinical pain, increased heat and mechanical temporal summation and poorer psychological function than those without NLP.

Why this matters

  • OA of the knee is considered a localized joint disease with peripheral nociceptive input; however, this study supports central sensitization.