Clinical progression of Lewy body dementia is detectable and quantifiable over 6 months

Takeaway

  • Progression of clinical features in Lewy body dementia can be detected over a 6-month period.

Why this matters

    Lewy body dementias are heterogenous disorders and the ability to determine disease progression through clinical measures is an urgent unmet need. The observation that clinically significant rates of change in core clinical features can be quantified in Lewy body dementia over 6 months suggests that these features could be used as clinical endpoints in therapeutic trials and for determining efficacy of disease modifying and symptomatic agents.