Clinical risk factors in SUDEP: A nationwide population-based case-control study


  • Individuals with generalized tonic-clonic seizures (GTCS) who sleep alone have an increased risk of sudden unexpected death in epilepsy (SUDEP), therefore there is a need for better supervision in high-risk patients with uncontrolled GTCS.

Why this matters

  • SUDEP is an important epilepsy-related cause of death, and is the second highest neurological disease when considering potential years of life lost.

  • In order to develop effective SUDEP prevention strategies and to guide patient counseling, the risk factors associated with SUDEP need to be elucidated in large, high-quality studies.