Comparing transorbital ultrasonography and conventional methods for assessing acute optic neuritis


  • Transorbital ultrasonography (TOUS) showed significant thickening of the optic nerve and sheath in patients with optic neuritis (ON) and an inverse relationship between TOUS features and onset of symptoms was observed.

Why this matters

  • Methods for assessing ON have inherent limitations (magnetic resonance imaging [MRI] can have limited availability and high cost, visual evoked potential [VEP] may not show symptoms in real time as VEP abnormality can exist after improvement of clinical symptoms, and retinal nerve fiber layer [RNFL] thickness assessed by optical coherence tomography [OCT] does not allow for structural assessment of the optic nerve) and, therefore, TOUS could be a cost-effective tool for evaluating ocular morphology during acute ON.