Consensus guidelines on glioblastoma contouring for radiation targeting


  • Following guidelines laid out in this article, a significant portion of brain can be spared from high-dose radiation.

Why this matters

  • Glioblastoma (GBM) is the most common primary brain malignancy in adults, and radiotherapy is an essential element of treatment; however, target delineation guidelines vary widely.

  • These guidelines will help reduce clinical uncertainty to improve tumor control and minimize unneeded radiotherapy toxicity.